SUPALIV
VIEW MOREInnovative supplement, whose component combination acts to alcohol metabolic cycle.
In 2003, at the harvest festival in famous winery of Count de Greiffenclau. A Japanese lady consulted with Markus Count Matuschka de Greiffenclau, host of the harvest festival. She loves wine but gets drunk soon.
Markus Count Matuschka knew that asian people are weak to drink alcohol and some of them cannot drink at all. He made a proposal to develop a supplement which would permit weak people to drink to enjoy wines.
Markus Count Matuschka consulted with his friend Haruhiko Inufusa (Physician, doctor of medicine) about developing an alcohol metabolism supplement.
Dr. Inufusa, who presented papers about the workings of alcohol and immune cells at academic conferences at that time, started to research alcohol metabolism.
After that, the research and development team led by Dr. Inufusa performed lots of clinical researches and acquired several patents.
SUPALIV was commercialized in 2011 and was on sell in Japan.
カンブリア宮殿(テレビ東京)をはじめ、NHK やフジテレビの番組にも多数出演。
Appeared on TV program “Cambria Palace” (TV Tokyo) and NHK and Fuji Television Network TV programs many times.
Member of Alliance Graphique Internationale, the world’s best designers’ organization.
JAGDA new face award, TDC award and many other awards.
By pursing arts of “printings that cannot be abandoned” and proposing “design as management resources” in stand on the point of views of both of manager and designer, he is supported by lots of clients from local small and medium-sized enterprises to foreign famous luxury brands.
On SUPALIV’s package, the crest of Count de Greiffenclau, who has carried on wine making from the age of Charlemagne, is printed.
This is because the research and development of SUPALIV were started by the proposal of Markus Count Matuschka de Greiffenclau, present chief director at European Medical Foundation TIMA Foundation and head of Count de Greiffenclau.
3 tablets
10 tablets
20 tablets
100 tablets bottle
Anti-aging supplement developed by the physician who has conduted antioxidant research for many years.
“Oxicut” was developed by the team led by Dr. Haruhiko Inufusa, specially appointed professor at the antioxidant division of Life Science Research Center, Gifu University. ICDD (French oxidative stress measuring company) certified Oxicut as the most antioxidant product in the world.
November 2007
Download PDF file “Twendee diabetes patients 3-months administration side effect survey”
November 2007
Download PDF file “Twendee toxicity test”
October 2007
Download PDF file “Twendee mutation test”
August 2007
Download PDF file “Twendee chromosomal aberration test”
May 2007
Download PDF file “Twendee toxicity preliminary test”
June 2021 第10回日本認知症予防学会学術集会”認知症予防の最先端”
September 2020 第61回日本神経学会学術大会”脳神経疾患の抗酸化治療 ー Twendee X 無限大の可能性ー”
October 2019 第1回日本脳サプリメント学会”抗酸化サプリメント Twendee Xの臨床効果”
December 2015 The 13th Meeting for Medical Use of Functional Foods, Fukuoka “Measuring Antioxidant Activity of Oxicut”.
November 2015 The 70th Meeting of the Coloproctology desease, Nagoya, Japan “Basic experiments of ulcerative colitis treatment with Oxicut, a new oxidative stress reduction combined supplement”.
June 2014 “Antioxidant effect that Oxicut gives to mouse radiation oxidative stress model”.
ビタミンC、ビタミンB群、アミノ酸、ラクトフェリンなど15種類の有用成分がバランスよく配合されたサプリメントです。
All the TIMA Japan products are certified to have effectiveness by a third party. Further, safety test, which is not ordinarily required for supplements, was also performed. We manufacture and sell only products with medically-proven effect (with evidence).
Safety test, ordinarily required only for pharmaceuticals, was performed by Ina Research Inc. (safety test trustee company, listed on the Tokyo Stock Exchange) in 2007 and all the tests conducted have reported SUPALIV is safe.
We have performed fundamental researches, animal experiments and human clinical trials about SUPALIV, and have given papers on these results at the 14th Anti-Aging Medicine meeting, the 12th Oxidative Stress and Antioxidant Seminar and other meetings.
Further, human clinical trial was performed by Allegro.Inc (subsidiary company of leading clinical examination company BML). The trial was performed twice in 2008 for cases of drinking vodka and wine.
Clinical trial’s result is here.
→Clinical Trial Result
Large number of international patents relating to SUPALIV and Twendee X are acquired or applied.
International Patent System (PCT) is useful in requesting international patent protection of applicant’s own invention(s). By applying one international patent, it becomes possible to request invention protection in 148 countries in the world at the same time.
About details of international patent, please refer to the following.
→ Acquired Patents